Usage, Warranty and Licenses

Usage

Research Purposes Only: Oligonucleotides and nucleic acid products ("IDT Products") are manufactured and sold by Integrated DNA Technologies, Inc. ("IDT") for the purchaser's research purposes only. Unless pursuant to a separate, written agreement with IDT, IDT Products are not sold (and have not been approved) for use in any clinical, diagnostic, or therapeutic applications. Obtaining any license(s) or other approvals necessary to use IDT Products in proprietary applications or in any non-research (e.g., clinical) applications is the purchaser's exclusive responsibility. IDT will not be responsible or liable for any losses, costs, expenses, or any other forms of liability arising out of the unauthorized or unlicensed use of IDT Products. By using any IDT Product for any purpose, purchasers and users of IDT Products agree to indemnify and hold IDT harmless for any and all damages and/or liability, however characterized, related to the unauthorized or unlicensed use of IDT Products. Under no circumstances shall IDT be liable for any consequential damages resulting from any use (approved or otherwise) of IDT Products. No Resale: The sale or resale of IDT Products by any person other than IDT is strictly prohibited without the express, written consent of IDT. IDT accepts all orders for and makes all sales of IDT Products subject to the foregoing use restrictions and the purchaser's indemnification of IDT.

Warranty

IDT's products are guaranteed to meet or exceed IDT's published specifications for identity, purity, and yield as measured under normal laboratory conditions. If an IDT Product fails to meet such specifications, IDT will promptly replace the product as purchaser's sole remedy for such failure. DISCLAIMER OF WARRANTIES – NO OTHER WARRANTIES: IDT makes no warranty of any kind whatsoever other than the foregoing General Warranty. Specifically, but without limitation, IDT expressly disclaims any implied warranties of merchantability or fitness for a particular purpose, and any warranty that IDT Products, or the use of IDT Products, will not infringe the patents of one or more third-parties. IDT accepts all orders for and makes all sales of IDT Products subject to the foregoing disclaimers of warranties.

Licenses/Trademarks

Fluorescent Labeled Oligonucleotides

Alexa Fluor® / Texas Red® / Bodipy® / Rhodamine Red™ and Rhodamine Green™ are provided under an agreement between Molecular Probes, Inc (a wholly owned subsidiary of Invitrogen Corporation), and Integrated DNA Technologies, and the manufacture, use, sale or import of this product may be subject to one or more U.S patents, pending applications, and corresponding non-U.S. equivalents, owned by Molecular Probes, Inc. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The buyer cannot sell or otherwise transfer (a) this product (b) its components or (c) materials made using this product o its components to a third party or otherwise use this product or its components or materials made using this product or its components for Commercial Purposes. Commercial Purposes means any activity by a party for consideration and may include, but is not limited to: (1) use of the product or its components in manufacturing; (2) use of the product or its components to provide a service, information, or data; (3) use of the product or its components for therapeutic, diagnostic or prophylactic purposes; or (4) resale of the product or its components, whether or not such product or its components are resold for use in research. For information on purchasing a license to this product for any other use, contact Molecular Probes, Inc., Business Development, 29851 Willow Creek Road, Eugene, OR 97402, USA, Tel: (541)465-8300. Fax: (541) 335-0504.

Black Hole Quenchers®, BHQ-1® and BHQ-2® , are trademarks of Biosearch Technologies, Inc. (BTI), and all BHQ products are licensed and sold under agreement with BTI. These products are sold exclusively for research and development use by the purchaser. They may not be used for any human or veterinary clinical or diagnostic purposes without express permission from BTI and they may not be re-sold, distributed, re-labeled or re-packaged.

Cy® Dyes. Cy® and CyDye® are registered trademarks of GE Healthcare.

IRDye® 700 and IRDye® 800 are products manufactured under license from LI-COR® Biosciences, which expressly excludes the right to use this product in AFLP applications.

IRDye 800 CW® is sold for research use only. Not for use in Diagnostic, Therapeutic or in human in-vivo applications. Not for commercial use. Other uses require a license from Li-Cor, Inc. under patents and patents pending in particular US Patent No. 6,995,274.

LightCycler® is sold under license from Roche Diagnostics GmbH.

TYE™ Dyes are sold under license from Thermo Fisher Scientific (Milwaukee) LLC.

Well-Red® Dyes: IDT manufactured oligonucleotides incorporating Well-Red® Dyes are made and sold under license from Beckman Coulter Inc., (BCI) for use exclusively with BCI instruments or BCI-approved instruments. All other uses are prohibited unless specifically and separately authorized by BCI.

PrimeTime® qPCR Probes and Assays: NOTICE TO PURCHASER: LIMITED LICENSE.

Use of this product is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,538,848, 5,723,591, 5,876,930, 6,030,787, 6,258,569, and 5,804,375 (claims 1-12 only). The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser's own internal research. Except under separate license rights available from Applied Biosystems, no right under any other patent claim, or to perform commercial services of any kind, including without limitation reporting the results of purchaser's activities for a fee or other commercial consideration, or to sublicense, repackage with other products, or resell in any form, is conveyed expressly, by implication, or by estoppel. This product is for research use only. Diagnostic uses under Roche patents require a separate license from Roche. Further information on purchasing licenses may be obtained from the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

Dual – Labeled Probes: NOTICE TO PURCHASER: DISCLAIMER OF LICENSE.

No license is conveyed with the purchase of this product under any of US Patents Nos5,804,375, 5,994,056, 6,171,785, 5,538,848, 5,723,591, 5,876,930, 6,030,787, and 6,258,569, and corresponding patents outside the United States, or any other patents or patent applications, relating to the 5’ Nuclease and dsDNA-Binding Dye Processes. For further information contact the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA

Molecular Beacons are licensed under patents owned by The Public Health Research Institute of the City of New York, Inc. and come with licensed rights for use only in the purchaser's research and development activities. A probe which has a hairpin (stem-and-loop) structure with a fluorophore, quencher, or other label on each arm of the hairpin stem is a Molecular Beacon Probe and must be ordered as a Molecular Beacon Probe. No license is conveyed with the purchase of this product under any of US Patents Nos. 5,804,375, 5,994,056, 6,171,785, 6,214,979, 5,538,848, 5,723,591, 5,876,930, 6,030,787, and 6,258,569, and corresponding patents outside the United States, or any other patents or patent applications, relating to the 5’ Nuclease and dsDNA-Binding Dye Processes. For further information contact the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.

Gene Knockdown

Chimeric Antisense Oligos In addition to the exclusive license under the University of Iowa Research Foundation patents, IDT is the sole oligonucleotide supplier licensed under several patents owned or presently controlled by ISIS Pharmaceuticals, Inc. to manufacture and sell Chimeric Antisense Oligonucleotides to universities and other non-profit institutions for research purposes. Certain design, sequence, scale and use restrictions may apply. IDT reserves the unlimited right to refuse any order for Chimeric Antisense Oligos.

Locked Nucleic Acids (LNAs) IDT is licensed under patents and patent applications assigned to Exiqon A/S to sell oligonucleotides incorporating LNAs for research purposes only. Resale of LNA-oligos and their use in humans or in therapeutic applications are all prohibited.

RNAi IDT's products are licensed under U.S. and international patent rights owned by the Carnegie Institution of Washington that cover RNA interference. These products are accompanied by a limited non-exclusive worldwide license under the Carnegie Institution of Washington's patent rights for researchers at academic or other not-for-profit institutions to use the products for non-profit research. However, use of dsRNA for RNA interference by for-profit organizations require a license from the Carnegie Institution of Washington.

siRNA This product is licensed under European Patents 1144623, 121945 and foreign equivalents from Alnylam Pharmaceuticals, Inc., Cambridge, USA and is provided only for use in academic and commercial research whose purpose is to elucidate gene function, including research to validate potential gene products and pathways for drug discovery and development and to screen non-siRNA based compounds (but excluding the evaluation or characterization of this product as the potential basis for a siRNA based drug) and not for any other commercial purposes. Information about licenses for commercial use (including discovery and development of siRNA-based drugs) is available from Alnylam Pharmaceuticals, Inc., 300 Third Street, Cambridge MA 02142, USA.

DsiRNA Duplexes IDT is exclusively licensed under patents owned by the City of Hope and IDT to make and sell DsiRNA Duplex products for use in research and development. Use of DsiRNA Duplex products or technology in humans or for human or veterinary diagnostic, prophylactic or therapeutic purposes requires a separate license from City of Hope Medical Center.

Other Disclaimers

Acrydite™. IDT is licensed under U.S. Patent Number 6,180,770, and 5,932,711 to sell oligos incorporating Acrydite™ modifications for use solely in the purchaser's own life sciences research and development activities. Resale, or use of this product in clinical or diagnostic applications, or other commercial applications, requires separate license from Matrix Technologies, Inc. Acrydite™ is a trademark of Matrix Technologies, Inc.

ATTO™ fluorescent dyes.  For research use only.  Resale, or use of this product in clinical or diagnostic applications, or other commercial applications, requires a separate license from ATTO-TEC GmbH.

Click-Chemistry enabled,
modified oligos are manufactured and sold under license from Baseclick GmbH, using Base-click's proprietary Click Chemistry. All such modified products are sold by IDT for the end-user's internal research purposes only. See www.baseclick.org for further details. 

Dithiol Modified Oligos, are protected by patents owned by FRIZ Biochem Gesellschaft für Bioanalytik mbH and may be used for research purposes only.

End-Blocked Oligos. This product is covered by US Patent No. 6,197,944 and sold under license from the University of Iowa Research Foundation for the customer's internal research purposes only.

Iso dC and Iso dG. IDT is licensed by Eragen Biosciences, Inc., under United States Patent Numbers 5,432,272; 6,001,983; 6,037,120; and 6,140,496, and other pending applications to sell oligonucleotides for non-commercial, research use in the life sciences research market.

RNaseAlert® compositions and methods are protected under U.S. Patent No. 6,773,885 and other pending IDT patent(s). RNaseAlert is a registered trademark of Ambion, Inc.

StarFire® compositions and methods are protected under U.S. Patent No. 6,773,885 and other pending IDT patent(s).

IDT requires that no apparel, garments or corresponding accessories, equipment, materials, or supplies furnished to IDT have been laundered or produced in whole or in part by inappropriate or unlawful means of labor in accordance with California Civil Code Section 1714.43 (California Transparency in Supply Chains Act) and Public Contract Code § 6108.

Trademarks

IDT Trademarks

DNaseAlert, Express DLP, gBlocks®, Hot Plate®, I-Linker, Iowa Black®, LabLinker®, Lockdown®, MAX, Mini Gene, Oligo Analyzer®, OligoCard®, PrimerQuest®, PrimeTime®, Rapid HPLC, Ready Made Primers, SameDay®, SciTools®, StarFire®, TEX 613, TYE, Ultramer®, xGen®

Other Trademarks

SYBR® Green and RNaseAlert® are registered trademarks of Life Technologies, Inc.

TaqMan® is a registered trademark of Roche Molecular Systems that is licensed exclusively to Applied Biosystems Inc. for use in certain non-diagnostics field.

Uni-Link™ is a trademark of Clontech Laboratories, Inc.