Many RNases and DNases are naturally found in the environment. Further, a variety of nucleases are employed in routine molecular biology methods and can accidentally contaminate lab surfaces at very high levels. In particular, RNases can be very difficult to eliminate and can cause damage to projects that require manipulations of intact RNA samples, such as functional genomics experiments, real-time quantitative PCR, microarrays, etc.
Nuclease Decontamination Solution irreversibly inactivates nucleases and can be applied to most lab surfaces to remove nuclease contamination. Just spray, rinse and let dry. Nuclease Decontamination Solution eliminates the need to bake glassware and can be applied to plastic surfaces which are difficult to sterilize.