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Frequently asked questions

Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.


SHERLOCK (Specific High sensitivity Enzymatic Reporter unLOCKing) is a method for detection of nucleic acid targets. It works by amplifying genetic sequences and programming a CRISPR molecule to detect the presence of a specific genetic signature in a sample.

When it finds that signature, the CRISPR enzyme gets activated and releases a detectable fluorescent signal.