2019 Novel Coronavirus (2019-nCoV)

IDT has received inquiries from researchers from around the world who are interested in rapidly obtaining assays and developing vaccines targeting the novel coronavirus (2019-nCoV/SARS-CoV-2) identified in Wuhan, China. Supporting these efforts, the CDC and the Chinese government have sequenced and submitted the coronavirus genome to the US NCBI GenBank® database [1]. With our worldwide manufacturing capabilities, IDT is uniquely able to provide robust qPCR assays while avoiding contamination issues from synthesis of controls and related gene fragments.

Virus detection

The US Centers for Disease Control and Prevention (CDC)* has designed RT-PCR assays and published a protocol for the detection of the 2019-nCoV [2,3]. IDT provides these CDC assays for the identification of virus. The assays are manufactured under ISO 13485:2016 conditions and are available for research use only (RUO). The kits containing these assays include primers and 5’ FAM / 3’ Black Hole Quencher® (BHQ) probes. 2019-nCoV controls** are available separately.

On February 4th, 2020, the FDA issued an Emergency Use Authorization to temporarily expand the use of assays to positively identify the coronavirus [4].


Ordering assays through our dedicated coronavirus channels ensures:

  • Fast shipping (1–2 business days)
  • ISO 13485:2016 standards of production
  • Most up-to-date CDC assay design
  • Preferred pricing

Don’t see what you need for your nCoV experiments?

We can accommodate custom requests.

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Vaccine development

Advances in gene synthesis mean that subunit vaccines can be developed quickly from one or more antigen-presenting viral genes or peptide sequences, which circumvents the need for scientists to handle live and potentially dangerous pathogens, and eliminates the time needed to clone DNA fragments.

Use IDT double-stranded DNA fragments to create synthetic proteins designed as safe reagents for vaccine research. IDT offers 3 convenient options: linear gBlocks Gene Fragments, eBlocks Gene Fragments, or Custom Genes cloned into vectors. These are available in varying lengths and synthesis scales. Start your order, and we will help you choose the format that best fits your needs.

Ordering synthetic gene fragments through our dedicated coronavirus channels ensures:

  • Priority shipping
  • Sequence verification
  • Preferred pricing

 

Ready to order?  Place your order using: https://www.idtdna.com/pages/products/genes-and-gene-fragments.  Upon confirmation of your order, please sign up using the “Sign Up” button and include your sales order number in the notes section.  A member of our Synthetic Biology Support Team will send a follow-up email confirming that preferred pricing and shipping have been added.

Looking for fast and safer reagents for your vaccine research?

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CDC Information for laboratories

Access the CDC’s latest laboratory guidance for 2019-nCoV RT-PCR assays.

* IDT is not, and does not claim to be, a primary, preferred or recommended source of the CDC coronavirus primer-probe panel.  IDT is independently offering an easy-to-order version of the panel of primer and probe sequences that were published by the CDC for use in coronavirus detection.

** The IDT controls have not been designed, tested, validated by CDC, nor are they in any way endorsed by the CDC or any other public health agency. These controls were independently designed by IDT against the entire nucleocapsid gene of SARS, MERS, and 2019-nCOV. These controls are offered as a convenience to our customers. Controls should be validated by the end-user if used for the interpretation of test results.

Information for laboratories

References

  1. (2020) 2019 Novel Coronavirus (2019-nCoV), Wuhan, China. [Online] US Centers for Disease Control and Prevention. [Accessed 28 Jan 2020].
  2. (2020) 2019-Novel coronavirus (2019-nCoV) real-time rRT-PCR panel primers and probes. US Centers for Disease Control and Prevention. [Accessed 28 Jan 2020].
  3. (2020) Real-time RT-PCR panel for detection 2019-novel coronavirus. US Centers for Disease Control and Prevention. [Accessed 28 Jan 2020].
  4. (2020) Emergency use authorization. [Online] US Centers for Disease Control and Prevention. [Accessed 28 Jan 2020].

Resources

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